|Synonyms||Azopyrin, Azulfidine, Sulfasalazin (DE), Sulfasalazina (ES), Sulfasalazine (FR/US)|
|Categories||Alimentary Tract and Metabolism, Analgesics, Anti-Inflammatory, Antirheumatic, Central Nervous System Agents, Gastrointestinal|
|Pharmacology||Crohn’s Disease (CD), Polyarticular Juvenile Rheumatoid Arthritis, Proctitis, Rheumatoid Arthritis, Severe Ulcerative Colitis, Mild Ulcerative Colitis, Moderate Ulcerative colitis|
Azulfidine is part of a category of medications called sulfa medicines and can be used to take care of pain and swelling in arthritis. It’s a mixture of salicylate (the primary ingredient in aspirin) as well as a sulfa antibiotic. Azulfidine is also called a disease-modifying anti-rheumatic drug (DMARD), because it not only reduces the pain and swelling of arthritis, but also might avoid injury to joints. Furthermore, it could decrease the possibility of long term decline of function.
Generic Azulfidine was used more than 70 years past to treat rheumatoid arthritis symptoms. At one time, atrophic arthritis was considered to result from a bacterial disease, and Sulfasalazine was approved, as it’s includes a mixture of an aspirin-like anti inflammatory medication using a sulfa including antibiotic. Sulfasalazine is still ideal for treating for light to moderate signs though we understand rheumatoid arthritis isn’t due to a bacterial disease, or could get for more serious symptoms of atrophic arthritis in addition to other medicines.
Additionally it is useful for other ailments, including:
- juvenile idiopathic arthritis (also also referred to as still’s disease)
- ankylosing spondylitis
- psoriatic arthritis
- reactive arthritis
- ulcerative colitis
The way that it operates
Azulfidine is a DMARD. DMARDs function to to diminish redness as well as pain, reduce/stop joint injury, and protect joint freedom. Sulfasalazine treats pain, swelling and stiffness . Nevertheless, it isn’t completely clear how this drug works for arthritis rheumatoid.
Azulfidine comes in a 500 milligram pill and needs to be used with a glass filled with water as well as food to prevent an upset belly. When managing rheumatoid arthritis symptoms to avoid negative effects, usually 1 to 2 pills a day the drug is usually started at reduced doses. Following the initial week, the dose might be slowly raised to the typical dosage of TWO tablets (1 g) twice a day. This dose could be raised to up to 6 tablets (3 grams) a day in a few scenarios. A Enteric-coated (or belly-coated) planning is available that could reduce a number of the unwanted effects linked with Azulfidine, especially indigestion. This kind of Azulfidine shouldn’t be crushed or chewed. The dose for some other circumstances, including ulcerative colitis, could vary.
It normally takes between 1 and A COUPLE OF MONTHS months after beginning sulfasalazine to see any improvement in rheumatoid arthritis symptoms signs.